The programme investigates contemporary longevity and healthcare technologies through the study of ageing biology, scientific evidence, medical innovation, personalised health and the ethical and social questions associated with life extension.
Programme Overview
The programme investigates contemporary longevity and healthcare technologies through the study of ageing biology, scientific evidence, medical innovation, personalised health and the ethical and social questions associated with life extension.
The Academy's academic model joins research methodology, advanced analytics, international professional practice and the continuous review of scientific and regulatory knowledge. The academic structure is organised around the programme’s principal research subjects and professional applications.
Academic research profile
Healthcare technologies and longevity research
Explore ageing biology, genetic and cellular technologies, digital health, sleep and metabolic science, public health environments and the ethical evaluation of emerging longevity interventions.
Intended research capabilities
Evaluate biomedical evidence without overstating efficacy; compare experimental and clinical research designs; distinguish approved clinical practice from experimental claims; formulate responsible, ethically sound research questions.
Teaching and research materials combine the Academy's four core dimensions: methodological design, critical analytics, comparative international practice and the review of current scientific and jurisdiction-specific evidence.
Open an academic unit to read its available study areas and programme outline. Select Expand all to display every section on this page.
0 of 18 curriculum sections open
Module 1Biology of Ageing and Fundamental Mechanisms of Life Extension+
Chapter 1Cellular senescence, telomeres and the replicative limit
Chapter 2Theories of ageing: free-radical, mitochondrial and epigenetic perspectives
Chapter 3Cellular restoration and DNA repair mechanisms
Chapter 4Information-based ageing: epigenetic clocks and their reversal
Chapter 5Hormesis, autophagy and biomarkers of healthy ageing
Chapter 6Research practice: investigating interventions with reported effects (caloric restriction, rapamycin and metformin)
Module 2Genetic Engineering and DNA Editing+
Chapter 1CRISPR/Cas9, prime editing and base editing technologies
Chapter 2Gene therapy: from rare diseases to ageing research
Chapter 3The human genome and opportunities to optimise gene expression
Chapter 4Anti-ageing experiments in animal models: SIRT, FOXO and Klotho
Chapter 5Ethical and regulatory frameworks for genome editing
Chapter 6Research practice: CRISPR case studies in longevity research
Module 3Rejuvenation Biotechnology and Cell Therapy+
Chapter 1Induced pluripotent stem cells (iPSCs)
Chapter 2Mesenchymal stem-cell therapies
Chapter 3Cellular reprogramming and Yamanaka factors
Chapter 4Exosomes and extracellular vesicles in regenerative research
Chapter 5Biochemical signalling in regeneration: GDF11, Klotho and eNAMPT
Chapter 6Research practice: laboratory and clinical applications
Module 4Food Technology and Nutrigenomics+
Chapter 1Institutional approaches to nutrition and longevity
Chapter 2Intermittent fasting, caloric restriction and fasting-mimicking protocols
Chapter 3Dietary supplements: NMN, resveratrol, sulforaphane and curcumin
Chapter 4Nutrigenomics and personalised nutrition
Chapter 5Epigenetic effects of diet on life expectancy
Chapter 6Research practice: dietary patterns in longevity populations (Blue Zones and Okinawa)
Module 5Metabolic Reprogramming and Endocrine Modulation+
Chapter 1Metformin, berberine and acarbose in geroscience pharmacology
Chapter 2Hormone therapy and balance: DHEA, melatonin and growth hormone
Chapter 3Mitochondrial function and NAD+ boosters
Chapter 4Diabetes as a model of accelerated ageing: prevention and remission
Chapter 5Testosterone, oestrogen and longevity: boundaries of therapeutic practice
Chapter 6Research practice: clinical approaches to metabolic regulation
Module 6Sleep Technologies and Circadian Medicine+
Chapter 1Molecular foundations of circadian rhythms and ageing
Chapter 2Sleep monitoring technologies: wearables, EEG and heart-rate variability
Chapter 3Light, temperature and melatonin in circadian regulation
Chapter 4Sleep restoration protocols: NREM and REM phases
Chapter 5Chronopharmacology and biological-clock optimisation
Chapter 6Research practice: sleep as a therapeutic research target in longevity
Module 7Breathing Practices, Yoga and Kinesiotherapy+
Chapter 1Breathing techniques: Buteyko, pranayama and Wim Hof methods
Chapter 2Yoga and mindfulness practices in biological-age research
Chapter 3Kinesiotherapy and neuroplasticity: physical and cognitive function
Chapter 4Movement practices for longevity: tai chi, qigong and Pilates
Chapter 5Physical activity, gene expression and metabolism
Chapter 6Research practice: physical-activity protocols in long-lived populations
Module 8Environmental and Urban Technologies for Longevity+
Chapter 1Urban environments and health: air, noise, greenery and lighting
Chapter 2Smart infrastructure and environmental quality monitoring
Chapter 3Air- and water-purification technologies from home to region
Chapter 4Biophilia, ecological design and psycho-environmental markers of longevity
Chapter 5Nutrition-related environments as external factors in longevity
Chapter 6Research practice: urban interventions, Singapore healthy cities and Blue Zones
Module 9Digital Health and Personalised Medicine+
Chapter 1Wearables and biomonitoring: from pedometers to ageing biomarkers
Chapter 2Digital twins: modelling and predicting human health
Chapter 3Biological-age prediction algorithms: Aging.AI, DeepAge and others
Chapter 4Personalised medicine: genotype, microbiome and behaviour
Chapter 5Artificial intelligence and big data in longevity analysis
Chapter 6Research practice: digital medicine case studies in longevity
Module 10Immunology of Ageing and Age-Related Therapeutic Approaches+
Chapter 1Immune ageing: immunosenescence and inflammageing
Chapter 2Vaccination and age-related infectious risks: CMV, herpes and other viruses
Chapter 3Senolytics and immunomodulators in ageing-related research
Chapter 4Thymus restoration, IL-7 and immune-system regeneration
Chapter 5The microbiome and immunity: the gut–brain–immune axis
Chapter 6Research practice: clinical research on TRIIM, Unity and thymus regeneration
Module 11Epigenetics and Molecular Clocks of Ageing+
Chapter 1Epigenetic clocks: Horvath, GrimAge and DNAmAge
Chapter 2Regulation of gene expression: HDAC inhibitors, diet and metabolites
Chapter 3DNA methylation and the effects of diet, stress and exercise
Chapter 4Epigenetic reprogramming: laboratory findings and future prospects
Chapter 5Epigenetic-clock diagnostics: from testing to interventions
Chapter 6Research practice: investigating biological-age reversal in humans (TRIIM and rejuvenation roadmaps)
Module 12Neuroprotection and Cognitive Longevity+
Chapter 1Neurodegeneration and brain ageing: mechanisms and vulnerability
Chapter 2Risk factors for cognitive decline: stress, glycaemia and hypoxia
Chapter 3Neuroprotective nutrients and compounds: omega-3, curcumin and citicoline
Chapter 4Brain training, BDNF, neuroplasticity and gamification
Chapter 5Dementia-prevention research: MIND diet and multimodal interventions
Chapter 6Research practice: preserved cognition in long-lived populations (SuperAgers and the Nun Study)
Module 13Psychology of Longevity and Stress Resilience+
Chapter 1Chronic stress, cortisol and accelerated ageing
Chapter 2Psychological resilience and longevity
Chapter 3Emotional health and affective characteristics of long-lived populations
Chapter 4Behavioural patterns: habits, discipline and self-perception
Chapter 5Meaning in life and ageing psychology: logotherapy and wellbeing
Chapter 6Research practice: psychology of longevity (Harvard Study and Blue Zones)
Module 14Sexual Health and Hormonal Regulation in Ageing+
Chapter 1Age-related changes in sexual function and libido
Chapter 2Hormonal regulation: testosterone, oestrogen, progesterone and DHEA
Chapter 3Hormone replacement therapy in ageing-related clinical practice
Chapter 4Sexual health and psycho-emotional wellbeing
Chapter 5Disease prevention and oncological risks in hormonal interventions
Chapter 6Research practice: clinical cases in sexual health and gerontology
Module 15Age-Related Pharmacology and Geroprotective Research+
Chapter 1Classification of geroprotectors: from metformin to glutathione
Chapter 2NAD+, NMN and NR in cellular energy metabolism
Chapter 3Rapamycin, mTOR and strategies to investigate the slowing of ageing
Chapter 4Sialic acids, peptides, senolytics and bioregulators
Chapter 5Biosafety, off-label prescribing and pharmacovigilance
Chapter 6Research practice: clinical studies and cases (TAME, PEARL and Rejuvenate Bio)
Module 16Cellular Markers and Bioinformatics of Ageing+
Chapter 1Cellular hallmarks of ageing: telomeres, SASP and mitochondria
Chapter 2Systemic biomarkers of ageing: CRP, HbA1c, IGF-1 and hs-TnT
Chapter 3Microbiome, metabolomics and markers of functional reserve
Chapter 4Omics technologies and personalised ageing profiles
Chapter 5Artificial intelligence and machine learning in gerontology
Chapter 6Research practice: constructing a digital profile of human ageing
Module 17Social Practices and Ethics of Life Extension+
Chapter 1Ageing as a social construction: image, roles and identity
Chapter 2The longevity economy: demography, pensions and active ageing
Chapter 3Digital inequality and access to ageing-related technologies
Chapter 4Ethical dilemmas of life extension: limits of intervention
Chapter 5Transhumanism, the posthuman and possible futures of human evolution
Chapter 6Research practice: regulatory and ethical decision-making (FDA, WHO and EU)
Module 18Futurology of Longevity and Designing Individual Life-Course Pathways+
Chapter 1Future scenarios: biomedicine, AI, neurointerfaces and synthetic biology
Chapter 2A personal longevity strategy: planning across the decades of life
Chapter 3Life-course architecture: work, education, family and longevity
Chapter 4Psychology of temporal perspective: thinking across a hundred-year lifespan
Chapter 5Future medicine and its integration into practice
Chapter 6Research practice: developing an individual longevity plan
Research Approach
Academic development begins with a clear research question and appropriate methodological design. Analytical models are examined alongside international cases and applicable jurisdiction-specific legal requirements. Scientific and regulatory claims are evaluated through source verification and continuing methodological review.
This page represents the Academy's programme development and intellectual property portfolio. Delivery, assessment and award of qualifications, where applicable, are separate institutional responsibilities.
